Betadine microbicides are effective against major vaginal pathogens. Betadine maintains microbicidal activity in the presence of blood, pus and vaginal secretions. Betadine antiseptic vaginal douche possess the complete broad spectrum microbicidal activity against all pathogenic organisms which commonly cause: any specific and unspecific vaginitis, all mixed infections including chlamydia, mycoplama, herpes, candida albicans and trichomonas vaginalis.